Endocrine Abstracts

Introduction: Vitamin D plays an essential role in calcium homeostasis and bone metabolism, immune modulation, and control of other hormonal systems. Vitamin D deficiency is also common for many reasons. On the other hand, thyroid diseases have widespread systemic manifestations including their effect on bone metabolism.Aim: To assess vitamin D status among Egyptian patients with different thyroid states: euthyroid, hypothyroid, or hyperthyroid states.</...

Objective: Assess the effect of bariatric surgery on serum glucagon like peptide-1 (GLP-1) concentration and metabolic and biochemical parameters pre and postoperatively.Methods: This prospective study comprised 50 subjects divided into 3 groups. Group 1: 20 obese subjects with T2DM (BMI >35) that underwent Roux-en-y gastric bypass surgery; Group 2: 20 lean subjects with T2DM and Group 3: 10 lean subjects as healthy controls.Bo...

Background: Visceral fat-derived protein named visfatin was discovered in 2005. Visfatin may improve glucose tolerance, and its plasma levels correlate strongly with the amount of visceral adipose tissue in humans. Visfatin has insulin-like metabolic effects on glucose metabolism but has a distinct binding site on insulin receptors. These findings triggered great interest for many researchers to explore the mechanism(s) of regulation of visfatin expression, and the possible re...